Other possible side effects include lightheadedness, fatigue, bowel changes, and muscle cramps. Spirolactone is a potassium sparing diuretic. If the pain is unbearable and persists for a long time, then it is better to consult a doctor. Muscle cramps are also a significant side effect that shouldn't be ignored. Diuretics are very important. Common side effects: Frequent urination; Tiredness or weakness; Muscle cramps The electrolyte shifts that happen on the low-carb diet are largely the result of the loss of salt … There may be tenderness on touching the muscle with ones hands. muscle cramps can also occur as a side effect of some drugs. With the notable (and relatively rare) exceptions of serious electrolyte imbalances including hypokalemia, hypomagnesemia and hypocalcemia, these cramps are typically benign in nature. In addition to increased age, other risk factors for the development of muscle cramps include peripheral neurological disease and peripheral vascular disease,2 including venous insufficiency,3 as well as arthritis, female gender,4 and hemodialysis. Thus, the combination of quinine and diuretics mandates extra vigilance in the monitoring of serum electrolytes. The first such study was a retrospective chart review of 50 patients who had been prescribed quinine to treat cramps, compared with 50 age‐matched controls.2 It is difficult to exclude an association between diuretics and muscle cramps from this retrospective study because of its small size and the presence of a selection bias. Medication Use and Functional Status Decline in Older Adults: A Narrative Review. Dr. Bennett Werner answered. They are spawned by an involuntary contraction of a muscle that will not relax. A muscle cramp (charley horse) is a sudden, brief, involuntary, painful contraction of a muscle or group of muscles. If the symptoms are unrelated to these factors, treatment with quinine—with careful attention to its risks—may be helpful. Potent diuretic medications, such as furosemide , or the vigorous removal of body fluids, even with less potent diuretics, can induce cramps by depleting body fluid and sodium. Copyright © 2020 Leaf Group Ltd., all rights reserved. Journal of the American Geriatrics Society. In fact, the Physicians' Desk Reference lists “muscle cramps or spasms” as an adverse effect with an incidence of ≥5% for indapamide, a thiazide‐like indoline diuretic. Taking Diuretics helps the heart pump better by lowering the extra fluids due to the dilated cardiomyopathy. Potassium is one electrolyte that has to be continuously replaced. Hypokalemia. Background: Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. Having a low potassium level can have serious health consequences. Drinking alcohol acts like a diuretic. Harvard Health Publishing. Making sure you stay well-hydrated also can help. In addition to getting rid of extra salt in your body, diuretic medications also affect levels of potassium. Their etiology is unclear, and an association with diuretic agents is possible. Examples include some diuretics, blood pressure medications, insulin, and cholesterol medications. The cramping is so bad that I am forced to use Spirivia instead. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. can high dose diuretics cause severe muscle cramps, low iron and low iron saturation? Brown CW, Deng JS "Thiazide diuretics induce cutaneous lupus-like adverse reaction." Numerous medicines can cause cramps. It is easy to self-diagnose muscle spasms and cramps. This can make you tired or weak or give you muscle cramps or a headache. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use, Clinical epidemiology of nocturnal leg cramps in male veterans, Prevalence and characteristics of muscle cramps in patients with varicose veins, Leg cramps in the elderly: prevalence, drug and disease associations, Meta‐analysis of efficacy of quinine for treatment of nocturnal leg cramps in elderly people. Quinine sulfate has been used extensively for this purpose for over 60 years. Important because it can cause muscle cramps over six years that can help you reduce chances... Bad that I am forced to use Spirivia instead, https:.. Extra vigilance in the calf muscles … you can usually treat muscle cramps are diuretic muscle cramps of diuretic and! 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